Organic Letters
Letter
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(16) At the present, the “inner-sphere type” approach deriving from
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(18) The presence of the in situ formed PPh3Au-O-naphthyl adduct
was ruled out by NMR analysis (see the Supporting Information).
(19) Adventitious traces of water in the NMR analyses led to the
formation of α-[PPh3Au]-acrolein intermediate: Mastandrea, M. M.;
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(7) For general reviews on the topic see: (a) Jia, M.; Bandini, M.
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(11) Performing the model reaction on 1 mmol scale of 1a in the
presence of PPh3AuCl/AgOTf (2.5 mol%), 3aa was isolated in 88%
yield after 3 h.
(12) The following allenamides proven ineffective under optimal
conditions.
(13) (a) Hashmi, A. S. K.; Hubbert, C. Angew. Chem., Int. Ed. 2010,
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