Journal of Pharmaceutical Sciences p. 1175 - 1178 (1976)
Update date:2022-08-11
Topics:
Indelicato
Wilham
Cerimele
The rate of hydrolysis of the formyl moiety of cefamandole nafate was determined as a function of pH, temperature, and concentration of added sodium carbonate or tromethamine. The reaction rate was sensitive to hydroxide ion in the pH 5.5-8.0 range with half life values of hours to minutes. Hydrolysis was rapid upon the addition of sodium carbonate or tromethamine. Chirality in the 7 D mandelamido side chain was unaffected by hydrolysis.
View MoreZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO.,LTD
Contact:+86-452-6055586
Address:5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
website:http://www.trustwe.com
Contact:+86-21-61551611
Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong
Changzhou Chenqiang Chemical Co., Ltd
website:http://www.cq-chem.com
Contact:+86-519-88902455
Address:Shanghuang Town, Liyang City
Nanjing Xi Ze Biological Technology Co., Ltd
Contact:86-025-66023220
Address:Address: Nanjin Qixia District Maigaoqiao R & D base in Pioneer Park Chun Yin Road 18-A928
Wuhan Yitongtai Science and Technology Co.,Ltd.
Contact:+86-27-88933550
Address:27th Fl. Bldg. 1, Shuian International Mansion, Heping Ave, Wuhan, Hubei, China
Doi:10.1002/chem.200500746
(2005)Doi:10.1016/j.tetlet.2008.02.107
(2008)Doi:10.1021/ja00308a046
(1985)Doi:10.1002/poc.688
(2004)Doi:10.1016/j.jallcom.2020.157348
(2021)Doi:10.1246/bcsj.58.2082
(1985)