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Scheme 2 Plausible reaction mechanism for the oxidative iodination of
alkynes.
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Conclusions
7
For selected examples, see: (a) G. D. Sun, M. J. Wei,
Z. H. Luo, Y. J. Liu, Z. J. Chen and Z. Q. Wang, Org. Process
Res. Dev., 2016, 20, 2074; (b) D. Wang, S. Chen and B. H.
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In conclusion, we have developed an efficient and mild approach
for the synthesis of trans-diiodoalkenes from alkynes in a highly
selective manner under oxidative iodination conditions. This
method operates under mild conditions and employs cheap,
commercially available and non-toxic inorganic salts as reagents
and water as a green solvent. The scope of the reaction has been
demonstrated with various alkynes such as aromatic, aliphatic
and hetero aromatic alkynes. Furthermore, the synthetic practic-
ability of the method has been established by performing gram-
scale experiments (up to 5 g scale) under standard conditions.
(
d) L. Luo., D. Resch, C. Wilhelm, C. N. Young, G. P. Halada,
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(a) M. Nechab, D. Campolo, J. Maury, P. Perfetti, N. Vanthuyne,
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Conflicts of interest
(
b) M. Kar and A. Basak, Chem. Rev., 2007, 107, 2861;
c) N. H ´e naff and A. Whiting, J. Chem. Soc., Perkin Trans. 1,
000, 395; (d) K. C. Nicolaou, A. L. Smith and E. W. Yue, Proc.
There are no conflicts to declare.
(
2
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We thank the DST, New Delhi for financial support under
the Indo-Russia (DST-RSF) (No. INT/RUS/RSF/P-7) programme.
B. R., P. S. and K. S. acknowledge the UGC, India and C. D.,
G. K. S. and Y. D. acknowledge the CSIR, India for financial
support in the form of fellowships.
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