Journal of Inorganic and General Chemistry
ARTICLE
Zeitschrift für anorganische und allgemeine Chemie
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ments were carried out in dimethylformamide solution of the complex
(1 mM) in a nitrogen atmosphere at room temperature.
SOD-like Activity: Superoxide anion (O2·–) was generated in enzy-
matic (xanthine/xanthine oxidase) system in the presence or absence
of test complex, and O2·– production was determined by monitoring
the reduction of NBT to monoformazan dye at 560 nm at 298 K.[45,40]
An appropriate amount of xanthine oxidase was added to a mixture of
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50 mm phosphate buffer (pH 7.8) to cause a variation of absorbance
(ΔA560/Δtmin) of 0.025Ϯ0.005. The percentage inhibition (% I) of
NBT+ formation was calculated from equation: (%) I = (A0 – As)/
A0 ϫ100, in which A0 and As are the maximum absorbance values due
to NBT+ at 560 nm in the absence and in the presence of the complex.
By plotting the% I as a function of complex concentration, the IC50
values were calculated.
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Kinetics of pNA Hydrolysis: The hydrolysis rate of pNA in the pres-
ence of complex was measured by an initial slope method following
the increase in the 400 nm absorption of the released p-nitrophen-
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adjusted to 0.10 with NaClO4.In a typical experiment, after substrate
(pNA) and complex in 10% (v/v) CH3CN solution at an appropriate
pH were mixed, the UV absorption decay was recorded immediately
and was followed generally until 2% decay of p-nitrophenyl acetate.
Errors on kobs values were about 5%.
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Crystallographic data (excluding structure factors) for the structure in
this paper have been deposited with the Cambridge Crystallographic
Data Centre, CCDC, 12 Union Road, Cambridge CB21EZ, UK.
Copies of the data can be obtained free of charge on quoting the de-
pository number CCDC-858595 (Fax: +44-1223-336-033; E-Mail:
deposit@ccdc.cam.ac.uk, http://www.ccdc.cam.ac.uk).
3245.
Supporting Information (see footnote on the first page of this article):
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Infrared spectra, UV/Vis spectra, ESI-MS of the ligand and the cop-
per(II) complex, and H NMR spectrum of the ligand.
1
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Acknowledgements
This work was supported by the National Natural Science Foundation
of China (No. 20901002), and Special and Excellent Research Fund
of Anhui Normal University.
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