Tetrahedron p. 5713 - 5726 (1988)
Update date:2022-08-10
Topics:
Kawasaki, Motoji
Matsuda, Fuyuhiko
Terashima, Shiro
The chiral synthesis of the (+)-naphthoquinone (4), the CDEF-ring system of nogalamycin congeners, has been accomplished following the synthetic scheme developed for the model (-)-DEF-ring system (3) in the preceding paper.This synthesis features (1) stereoselective construction of the C5'-asymmetric center by introducing the naphthalene moiety into the (-)-methyl ketone (5), the glycoside part, (2) regioselective oxidation of the 1,4,5,8-tetramethoxynaphthalene moiety with cerium(III) ammonium nitrate, and (3) efficient formation of bicyclic acetal system.
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Doi:10.1016/j.poly.2019.114309
(2020)Doi:10.1021/jo970047b
(1997)Doi:10.1021/jo00946a020
(1973)Doi:10.1016/j.tet.2006.02.013
(2006)Doi:10.1007/BF02038707
()Doi:10.1007/BF00522143
(1982)