Org aP nl ei ca s &e dB oi o nmo to al ed cj uu sl at rm Ca hr ge imn si stry
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ARTICLE
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nucleophiles gave either no reaction or low enantioselectivity.
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6
,
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42−446; (e) F.-S. He, J.-H. Jin, Z.-T. Yang, X. Yu, J. S. Fossey 10 Chiral naphthol-containing molecules, such as BINOL and its
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As shown below, low enantioselectivity was obtained under 11 Catalyst C3 was first reported by List and co-workers: S. Muller,
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The nucleophiles we evaluated include indole, 1,3,5-
trimethoxybenzene, phenol and substituted phenols, 1,3-
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