Synthetic Communications p. 1133 - 1141 (1997)
Update date:2022-08-28
Topics:
Kumar, Ashok
Rane, Ramkrishna A.
Ravindran, Vaikyparambil K.
Dike, Suneel Y.
1,2-Aryl migration of 1-halomethyl-2-(4-hydroxyphenyl) ketals, obtained from 2-bromomethyl 4-hydroxyacetophenone, under mild basic conditions have been shown to give 4-hydroxyphenylacetic acid or its derivatives which are key intermediates in the preparation of Atenolol, a well known cardiac β-blocker.
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