Research on Chemical Intermediates p. 6601 - 6616 (2017)
Update date:2022-08-16
Topics:
Rajput, Jamatsing D.
Bagul, Suresh D.
Bendre, Ratnamala S.
In present work, we report the synthesis of 12 new hydrazones and sulfonyl hydrazones linkage containing carvacrol, thymol and eugenol derivatives by simple condensation reactions. Synthesized derivatives have been characterized by 1H NMR, 13C NMR, LC–MS, and X-ray single crystallography techniques, and these derivatives were screened for anticancer testing by using sulforhodamine B assay and anti-oxidant testing by using DPPH assay. Docking studies of all the derivatives against the active site of human heme oxygenase-1 indicated that interaction with the maximum site of the amino acid residue of human heme oxygenase-1 was crucial for anti-oxidant activity. The results show that all derivatives possess interesting biological activities.
View MoreChengdu ZY Biochemical Technology Co., LTD
Contact:0086-28-88680086
Address:170 Qingpu Road, Shouan Town, Pujiang County
Anyang Double Circle Auxiliary CO.,LTD
Contact:0086-134 6082 4403
Address:dongfeng road, anyang city, henan province,china
Shanghai Anya Chemicals Co.,Ltd
Contact:+86 21 51087925
Address:Room 1101, No.1, Lane 111, Fudu Road, Shanghai, China
Synochem Ingredients Corp., Ltd.
Contact:+86-512-5636 2180
Address:Zhangjiagang Free Trade Zone
SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD
Contact:+86-311-85208698 311-80837698
Address:NO.166, yuhua west road, SHIJIAZHUANG, China
Doi:10.1080/10426501003598671
(2010)Doi:10.1016/j.ica.2021.120560
(2021)Doi:10.1021/ol701851f
(2007)Doi:10.1021/acscatal.6b03441
(2017)Doi:10.1107/S1600576717012316
(2017)Doi:10.1016/j.bmcl.2016.03.045
(2016)