Macromolecules p. 7109 - 7114 (2011)
Update date:2022-08-11
Topics:
Chen, Bo
Deng, Jianping
Cui, Xin
Yang, Wantai
Helical substituted polyacetylenes were investigated for inducing enantioselective crystallization of racemic N-(tert-butoxycarbonyl)alanine (BOC-alanine) enantiomers. For this purpose, helical substituted polyacetylenes [(R)-PSA and (S)-PSA)] were dissolved in supersaturated racemic BOC-alanine solutions. Upon cooling the solutions, (R)-PSA preferentially induced BOC-l-alanine to crystallize, while (S)-PSA facilitated the enantioselective crystallization of BOC-d-alanine, according to the characterizations by circular dichroism, XRD, SEM, and optical rotation analyses. As expected, no enantioselective crystallization was observed in such cases: racemic BOC-alanine enantiomers in the absence of optically active helical PSA and racemic BOC-alanine enantiomers in the presence of equal amount of (R)-PSA and (S)-PSA. The present study provides the first direct evidence for the role of artificially synthetic helical polymers in inducing efficiently enantioselective crystallization.
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Doi:10.1055/s-1984-30785
(1984)Doi:10.1021/jo00920a020
(1974)Doi:10.1016/j.apcata.2018.07.006
(2018)Doi:10.1016/S0040-4020(01)01131-0
(2002)Doi:10.1007/s11164-016-2517-8
(2016)Doi:10.1055/s-1984-30986
(1984)