Carbothioamide, 1,2,4-triazole, 1,3,4-thiadiazole 973
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, triazole (3a–n) and thiadiazole derivatives (4a–g) were
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generally more active than the hydrazinecarbothioamide
derivatives (2a–d). e antimicrobial activity results
indicated that some of the tested compounds showed the
most promising antibacterial and antifungal activities.
In summary, a new series of hydrazinecarbothio-
amides 2a–d, 1,2,4-triazoles 3a–n, and 1,3,4-thiadiazoles
2
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a–g have been synthesized and evaluated for their anti-
1
1
bacterial and antifungal activities. Derivatives 3c (R = H,
R′ = C H ), were most active against M. gypseum NCPF
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crobial activity results indicated that some of the tested
compounds showed the most promising antibacterial
and antifungal activities. Further studies are in progress
in our laboratories and will be reported upon in the
future.
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