Organic Letters
Letter
lysosome), respectively (Figures 5b and S13). The merged
image indicated that the OXN-1 is mainly localized in the
lysosome that has slightly acidic pH, presumably due to the
amine moieties in the structure.
Next, we demonstrated the two-photon tissue imaging ability
of OXN-1. With the sizable two-photon action cross-section
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ASSOCIATED CONTENT
Supporting Information
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*
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and characterization; H and C NMR spectra (PDF)
AUTHOR INFORMATION
■
ORCID
Author Contributions
◆
These authors contributed equally.
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
■
This research was supported by the Bio & Medical Technology
Development Program of the NRF of Korea funded by the
Ministry of Science & ICT (2018-M3A9H3021707). This
research was also supported by Basic Science Research Program
through the NRF of Korea funded by the ministry of Education
(
2018-R1A6A1A03025124, 2018-R1D1A1B07043383).
B.M.K. thanks the financial support from the NRF of Korea
2012-M3A7B4049644). S.P. thanks the financial support from
the NRF of Korea (2016-R1A2B4011522).
(
D
Org. Lett. XXXX, XXX, XXX−XXX