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[23] Because of the low solubility of the lyso-PC, toluene, the
standard solvent for the Yamaguchi reaction, was not used.
[24] Prepared from racemic glycidol according to
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a literature
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sequence of reactions: 1) aldol reaction of 7 with MeO2C-
=
(CH2)3CH CHCHO; 2) epoxidation of the resulting anti aldol
product with tBuOOH/Ti(OiPr)4; 3) mesylation; 4) elimination
of the mesylate group with Al2O3.
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Angew. Chem. Int. Ed. 2005, 44, 3481 –3484