Tetrahedron p. 8545 - 8554 (1995)
Update date:2022-08-17
Topics:
Del Bosco, Marco
Johnstone, Andrew N.C.
Bazza, Giorgia
Lopatriello, Stefania
North, Michael
Treatment of α-t-butyl γ-methyl N-Z glutamate with lithium hexamethyldisilazide gives the γ-enolate regioselectively. Reaction of this enolate with electrophiles gives γ-substituted glutamic acid derivatives including the conformationally constrained glut
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