ChemComm
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Journal Name
COMMUNICATION
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0
1
2
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1
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16 Attempts to improve the ratio of mono- and di-halogenated
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,
3
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TOC
O
O
X
PIP 20 mol% CuX
PIP
Ar/
Het
N
Ar/
Het
N
R
H
R
H
PIP =
NXS
H
N
31 examples
up to 97% yield
catalytic copper catalyst ?compatible with electron-rich and electron-deficient arenes
ortho-selectivity ?gram scale halogenation (5 mmol)
X = Cl, Br, I
?
?
?compatible with heteroarenes
4
| J. Name., 2012, 00, 1‐3
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