258
D.Yıldırım & S. S.Tükel
kołodziejska r, karczmarska-Wódzka a,Wolan a, Dramin´ski m.
2012. Candida antarctica lipase B catalyzed enantioselective
acylation of pyrimidine acyclonucleoside. Biocatal Biotrans-
form 30:426–430.
lee B-m, Choi J-h, hong Sı,Yoon SW, kim Bh, kim C-T, et al.
2011. enrichment of pinolenic acid from pine nut oil via lipase-
catalyzed ethanolysis with an immobilized Candida antarctica
lipase. Biocatal Biotransform 29:155–160.
levinson We, kuo Tm, kurtzman CP. 2005. lipase-catalyzed
production of novel hydroxylated fatty amides in organic
solvent. enzyme microb Technol 37:126–130.
li G-Y, huang k-l, JiangY-r, Ding P. 2007. Production of (r)-
mandelic acid by immobilized cells of Saccharomyces cerevisiae
on chitosan carrier. Process Biochem 42:1465–1469.
litjens mJ, Sha m, Straathof aJ, Jongejan Ja, heijnen JJ. 1999.
Competitive lipase-catalyzed ester hydrolysis and ammoniolysis
in organic solvents; equilibrium model of a solid–liquid–vapor
system. Biotechnol Bioeng 65:347–356.
References
alptekin Ö, Tükel SS, Yildirim D, alagöz D. 2011. Covalent
immobilization of catalase onto spacer-arm attached modified
florisil: Characterization and application to batch and plug-flow
type reactor systems. enzyme microb Technol 49:547–554.
Bai zW, zhou Yk. 2004. a novel enzyme support derived from
aminated silica gel and polysuccinimide: preparation and appli-
cation for the immobilization of porcine pancreatic lipase. react
Funct Polym 59:93–98.
Borch rF, Bernstein mD, Durst hD. 1971. Cyanohydridobo-
rate anion as a selective reducing agent. J am Chem Soc 93:
2897–2904.
Bornscheuer UT. 2002. methods to increase enantioselectivity of
lipases and esterases. Curr Opin Biotechnol 13:543–547.
Cabrera z, Fernandez-lorente G, Fernandez-lafuente r,
Palomo Jm, Guisan Jm. 2009. novozym 435 displays very
different selectivity compared to lipase from Candida antarctica
B adsorbed on other hydrophobic supports. J mol Catal B
enzym 57:171–176.
liu k-J. 2009. lipase-catalyzed synthesis and antibacterial
activity of n-vanillylnonanamide. J mol Catal B enzym 58:
181–186.
lowry Oh, rosebrough nJ, Farr al, randall rJ. 1951. Protein
measurement with the folin phenol reagent. J Biol Chem
193:265–275.
CaoY, Wu S, li J, Wu B, he B. 2014. highly efficient resolution
of mandelic acid using lipase from Pseudomonas stutzeri lC2-8
and a molecular modeling approach to rationalize its enantiose-
lectivity. J mol Catal B enzym 99:108–113.
Chang C-S, Su C-C, zhuang J-r, Tsai S-W. 2004. enhancement
of enantioselectivity on the synthesis of (S)-naproxen mor-
pholinoalkyl ester prodrugs in organic solvents using isopropanol-
dried immobilized lipase. J mol Catal B enzym 30:151–157.
Chen C-S, Fujimoto Y, Girdaukas G, Sih CJ. 1982. Quantitative
analyses of biochemical kinetic resolutions of enantiomers.
J am Chem Soc 104:7294–7299.
Coppola Gm, Schuster hF. 1997. a-hydroxy acids in enantiose-
lective syntheses. Weinheim: Wiley-VCh Verlag Gmbh & Co.
kGaa.
mitsuya m, kobayashi k, kawakami k, Satoh a, Ogino Y,
kakikawa T, et al. 2000. a potent, long-acting, orally active
(2R)-2-[(1R)-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenyla-
cetamide: a novel muscarinic m3 receptor antagonist with
high selectivity for m3 over m2 receptors. J med Chem 43:
5017–5029.
nordblad m, adlercreutz P. 2013. ımmobilisation procedure and
reaction conditions for optimal performance of Candida ant-
arctica lipase B in transesterification and hydrolysis. Biocatal
Biotransform 31:237–245.
Couturier l, Taupin D, Yvergnaux F. 2009. lipase-catalyzed
chemoselective aminolysis of various aminoalcohols with fatty
acids. J mol Catal B enzym 56:29–33.
Gotor-Fernández V, Gotor V. 2008. aminolysis and ammonolysis
of carboxylic acid derivatives ın: Gotor V, alfonso ı, García-
Urdiales e, eds. asymmetric organic synthesis with enzymes.
Weinheim:Wiley-VCh Verlag Gmbh & Co. kGaa. pp. 171–191.
hirose h, aoki ı, kimura T, Fujikawa T, numazawa T, Sasaki k,
et al. 2001. Pharmacological Properties of (2R)-n-[1-(6-
aminopyridin-2-ylmethyl)piperidin-4-yl]-2-[(1R)-3,3-
Ong al, kamaruddin ah, Bhatia S, long WS, lim ST,
kumari r. 2006. Performance of free Candida antarctica lipase
B in the enantioselective esterification of (r)-ketoprofen.
enzyme microb Technol 39:924–929.
Palomo Jm, muñoz G, Fernández-lorente G, mateo C,
Fuentes m, Guisan Jm, Fernández-lafuente r. 2003. modula-
tion of Mucor miehei lipase properties via directed immobiliza-
tion on different hetero-functional epoxy resins: hydrolytic
resolution of (R,S)-2-butyroyl-2-phenylacetic acid. J mol Catal
B enzym 21:201–210.
difluorocyclopentyl]-2-hydroxy-2-phenylacetamide:
a
novel
Pawar SV,Yadav GD. 2014. enantioselective enzymatic hydrolysis
of rac-mandelonitrile to r-mandelamide by nitrile hydratase
immobilized on poly(vinyl alcohol)/chitosan–gutaraldehyde
support. ınd eng Chem res 53:7986–7991.
Persson m, Costes D, Wehtje e, adlercreutz P. 2002. effects of
solvent, water activity and temperature on lipase and hydrox-
ynitrile lyase enantioselectivity. enzyme microb Technol 30:
916–923.
ragupathy l, Pluhar B, ziener U, keller h, Dyllick-Brenzinger r,
landfester k. 2010. enzymatic aminolysis of lactones in aque-
ous miniemulsion: catalysis through a novel pathway. J mol
Catal B enzym 62:270–276.
Turcu mC, Perkiö P, kanerva lT. 2010. Chemoenzymatic
method for the preparation of g-amino alcohols from phenyl-
furan-based aldehydes; lipase-catalyzed kinetic resolution of
b-hydroxy nitriles. Tetrahedron asymmetr 21:739–745.
Yadav GD, Sivakumar P. 2004. enzyme-catalysed optical
resolution of mandelic acid via rS( )-methyl mandelate in non-
aqueous media. Biochem eng J 19:101–107.
-sparing antagonistic activity.
muscarinic antagonist with m2
J Pharmacol exp Ther 297:790–797.
huang h-r, Xu J-h. 2006. Preparation of (S)-mandelic acid from
racemate using growing cells of Pseudomonas putida eCU1009 with
(R)-mandelate degradation activity. Biochem eng J 30:11–15.
ırimescu r, kato k. 2004. lipase-catalyzed enantioselective reac-
tion of amines with carboxylic acids under reduced pressure in
non-solvent system and in ionic liquids. Tetrahedron lett
45:523–525.
Jin X, liu B, ni z, Wu Q, lin X. 2011. a novel control of
enzymatic enantioselectivity through the racemic temperature
influenced by reaction media. enzyme microb Technol 48:
454–457.
kaul P, Banerjee a, mayilraj S, Banerjee UC. 2004. Screening for
enantioselective nitrilases: kinetic resolution of racemic man-
delonitrile to (r)-()-mandelic acid by new bacterial isolates.
Tetrahedron asymmetr 15:207–211.
khare Sk, kumar a, kuo Tm. 2009. lipase-catalyzed produc-
tion of a bioactive fatty amide derivative of 7,10-dihydroxy-
8(E)-octadecenoic acid. Bioresour Technol 100:1482–1485.
klibanov am. 2001. ımproving enzymes by using them in organic
solvents. nature 409:241–246.
Yildirim D, Tükel SS. 2013. ımmobilized Pseudomonas sp. lipase:
a powerful biocatalyst for asymmetric acylation of ()-2-
amino-1-phenylethanols with vinyl acetate. Process Biochem
48:819–830.