Tetrahedron Letters p. 1767 - 1768 (1994)
Update date:2022-08-10
Topics:
Zikos, Christos C.
Ferderigos, Nicolas G.
Novel trityl type handles have been prepared and applied to solid phase synthesis using 9 - fluorenylmethyloxycarbonyl (Fmoc) for Na - amino protection and acid labile protecting groups for side chain protection. The cleavage of the resultant ester can be carried out by using appropriate mild acidic cocktails 0.1 % (v/v) trifluoroacetic acid, and TFE : CH2Cl2 : CH3COOH 1: 8 : 1 (v/v).
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Doi:10.1055/a-1282-9731
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(1995)