Phosphorus, Sulfur and Silicon and the Related Elements p. 1621 - 1627 (2005)
Update date:2022-08-10
Topics:
De, Qing Shi
Chen, Qi
Zhong, Hua Li
Xiao, Peng Liu
A series of novel phosphoramide-tegafur derivatives containing γ-aminopropyl silatrane were synthesized via the condensation reactions of phosphoryl dichloride with N1-(2-furanidyl)-N3- (hydroxyethyl)-5-fluorouracil, followed by condensation with γ-aminopropyl silatrane. The structures of the products were confirmed by 1H NMR, 31P NMR, IR, MS, and elemental analysis. The results of preliminary bioassay showed that the new compounds had an inhibition effect against HCT-8 and Bel-7402 cell lines. Copyright Taylor & Francis Inc.
View MoreChemvon Biotechnology Co. Ltd.
website:http://www.chemvon.com
Contact:86-21-58550039;86-21-31268550-8004
Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China
Shanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Changzhou naidechemical Co.Ltd
Contact:+86-519-82589807
Address:NO.25,Houyang street,Jintan,Changzhou City
Contact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Beijing Hope Pharmaceutical Co., Ltd.
Contact:86-10-67886402
Address:309,Block 1 District B,No.12 Hongda North Road , Beijing Economic-Technological Development Area, Beijing, China
Doi:10.1039/jr9560003333
(1956)Doi:10.1021/ja01589a078
(1956)Doi:10.1016/S0040-4039(00)89384-3
(1970)Doi:10.1016/j.bioorg.2016.08.005
(2016)Doi:10.1016/S0040-4039(00)94888-3
(1985)Doi:10.1016/0040-4039(92)80017-E
(1992)