Tetrahedron Letters p. 1631 - 1634 (1994)
Update date:2022-08-11
Topics:
Richter, Lutz S.
Marsters Jr., James C.
Gadek, Thomas R.
Two new methods for the benzylation of thiols are described: a) direct-S- alkylation with para-substituted benzylic cations; and b) reductive S- alkylations of 2-aminothiols. Both methods provide efficient routes for the introduction of benzyl-type protecting groups in high yields.
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