Journal of Organic Chemistry p. 7393 - 7399 (2016)
Update date:2022-08-11
Topics:
Niu, Guangle
Liu, Weimin
Zhou, Bingjiang
Xiao, Hongyan
Zhang, Hongyan
Wu, Jiasheng
Ge, Jiechao
Wang, Pengfei
In this work, two xanthene dyes (H-hNR and TF-hNR) have been synthesized by a convenient and efficient method. These two dyes exhibited deep-red and near-infrared emissions, high fluorescence quantum yields, and good photostability. Their structure-optical properties were investigated by X-ray crystal structure analysis and density functional theory calculations. Live cell imaging data revealed that H-hNR and TF-hNR could rapidly stain both A549 and HeLa cells with low concentrations. The excellent photophysical and imaging properties render them as promising candidates for use in live cell imaging.
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