Synthetic Communications p. 279 - 285 (2019)
Update date:2022-08-03
Topics:
Nagpal, Reshma
Bhalla, Aman
Bhalla, Jitender
Bari, Shamsher S.
Thapar, Renu
Facile and efficient synthesis of sulfoxide esters using menthols as chiral auxiliary is described. Phenylthio/benzylthio/naphthylthioacetic esters act as an efficient substrate for chiral sulfoxides via oxidation in one step. The structural and stereochemical aspects of target product were established on the basis of various spectroscopic studies, namely FT-IR, NMR (1H NMR and 13C NMR) and elemental analysis. This method is simple, fast, convenient and very efficient.
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