T. Abe et al. / Tetrahedron Letters 47 (2006) 8727–8730
8729
Scheme 2. Formation of 6-ethyl-4-hydroxy-3,5-dimethyl-2-pyrone by sequential decarboxylative condensations of three molecules of (2RS)-
methylmalonyl-CoA.
Aid for Scientific Research (Nos. 18510190 and
17310130), Cooperation of Innovative Technology and
Advanced Research in Evolutional Area (CITY AREA,
the Central Shizuoka Area), and the COE21 program
from the Ministry of Education, Culture, Sports,
Science and Technology, Japan.
References and notes
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Acknowledgements
This work was supported by the PRESTO program
from Japan Science and Technology Agency, Grant-in-