COMMUNICATIONS
or NiBr (PCy ) (19.6 mg, 0.025 mmol, 0.05 equiv.) and THF
f) Y. Yamamoto, M. Takizawa, X.-Q. Yu, N. Miyaura,
Angew. Chem. 2008, 120, 942–945; Angew. Chem. Int.
Ed. 2008, 47, 928–931; g) H. Noguchi, K. Hojo, M. Su-
ginome, J. Am. Chem. Soc. 2007, 129, 758–759.
2
3 2
(
2 mL) were added. After stirring for 5 min, H O (18 mL,
2
1
mmol, 2 equiv.) was added. The resulting mixture was
stirred at the appointed temperature for 12 h. After quench-
ing with water, the reaction mixture was extracted with
ethyl acetate. The organic layer was washed with brine and
then evaporated under vacuum. Flash chromatography on
silica gel yielded the cross-coupling products.
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[
9] For scattered reports of fluoro-containing arylboronic
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Acknowledgements
We gratefully thank the NSF (CHE0911533) and NIH (1R15
GM094709) for funding. Partial support from PSC-CUNY
Research Award Program is also gratefully acknowledged.
2
413; f) L. Zhang, T. Meng, J. Wu, J. Org. Chem. 2007,
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Adv. Synth. Catal. 0000, 000, 0 – 0
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