5
48
PHARMACOTHERAPY Volume 21, Number 5, 2001
1
997;87:1271–3.
33. Tramer MR, Reynolds DJM, Moore RA, McQuay HJ. Efficacy,
dose-response, and safety of ondansetron in prevention of
postoperative nausea and vomiting: a quantitative systematic
review of randomized placebo-controlled trials. Anesthesiology
1997;87:1277–89.
1
1
2
2
8. Khalil S, Philbrook L, Rabb M, et al. Ondansetron/
promethazine combination or promethazine alone reduces
nausea and vomiting after middle ear surgery. J Clin Anesth
1
999;11:596–600.
9. Fortney JT, Gan TJ, Graczyk S, et al. A comparison of the
efficacy, safety, and patient satisfaction of ondansetron versus
droperidol as antiemetics for elective outpatient surgical
procedures. Anesth Analg 1998;86:731–8.
0. American Society of Anesthesiologists Task Force on Pain
Management, Acute Pain Section. Practice guidelines for acute
pain management in the perioperative setting. Anesthesiology
34. Graczyk SG, McKenzie R, Kallar S, et al. Intravenous
dolasetron for the prevention of postoperative nausea and
vomiting after outpatient laparoscopic gynecologic surgery.
Anesth Analg 1997;84:325–30.
35. Korttila K, Clergue F, Leeser J, et al. Intravenous dolasetron
and ondansetron in prevention of postoperative nausea and
vomiting: a multicenter, double-blind, placebo-controlled study.
Acta Anaesthesiol Scand 1997;41:914–22.
1
995;82:1071–81.
1. Morrow GR. The assessment of nausea and vomiting: past
problems, current issues, and suggestions for future research.
Cancer 1984;53(suppl):2267–80.
36. Henzi I, Walder B, Tramer MR. Dexamethasone for the
prevention of postoperative nausea and vomiting: a quantitative
systematic review. Anesth Analg 2000;90:186–94.
2
2
2
2
2
2. Olver IN, Simon RM, Aisner J. Antiemetic studies: a
methodological discussion. Cancer Treat Rep 1986;70:555–63.
3. Gralla RJ, Clark RA, Kris MG, Tyson LB. Methodology in anti-
emetic trials. Eur J Cancer 1991;27(suppl):S5–8.
4. Watcha MF. The cost-effective management of postoperative
nausea and vomiting. Anesthesiology 2000;92:931–3.
5. White PF, Watcha MF. Postoperative nausea and vomiting:
prophylaxis versus treatment. Anesth Analg 1999;89:1337–9.
6. Hill RP, Lubarsky DA, Phillips-Bute B, et al. Cost-effectiveness
of prophylactic antiemetic therapy with ondansetron,
droperidol, or placebo. Anesthesiology 2000;92:958–67.
7. Frighetto L, Loewen PS, Dolman J, Marra CA. Cost-
effectiveness of prophylactic dolasetron or droperidol vs rescue
therapy in the prevention of PONV in ambulatory gynecologic
surgery. Can J Anesth 1999;46:536–43.
8. Tang J, Watcha MF, White PF. A comparison of costs and
efficacy of ondansetron and droperidol as prophylactic
antiemetic therapy for elective outpatient gynecologic
procedures. Anesth Analg 1996;83:304–13.
9. Watcha MF, Smith I. Cost-effectiveness analysis of antiemetic
therapy for ambulatory surgery. J Clin Anesth 1994;6:370–7.
0. Domino KB, Anderson EA, Polissar NL, Posner KL.
Comparative efficacy and safety of ondansetron, droperidol,
and metoclopramide for preventing postoperative nausea and
vomiting: a meta-analysis. Anesth Analg 1999;88:1370–9.
1. Helmy SAK. Prophylactic anti-emetic efficacy of ondansetron
in laparoscopic cholecystectomy under total intravenous
anaesthesia: a randomised, double-blind comparison with
droperidol, metoclopramide and placebo. Anaesthesia
37. Janknegt R, Pinckaers JWM, Rohof MHC, et al. Double-blind
comparative study of droperidol, granisetron and granisetron
plus dexamethasone as prophylactic anti-emetic therapy in
patients undergoing abdominal, gynaecological, breast or
otolaryngological surgery. Anaesthesia 1999;54:1059–68.
38. Splinter WM, Rhine EJ. Low-dose ondansetron with
dexamethasone more effectively decreases vomiting after
strabismus surgery in children than does high-dose
ondansetron. Anesthesiology 1998;88:72–5.
39. Fujii Y, Saitoh Y, Tanaka H, Toyooka H. Combination of
granisetron and droperidol in the prevention of nausea and
2
2
vomiting after middle ear surgery.
1999;11:108–12.
J Clin Anesth
40. Bugedo G, Gonzalez J, Asenjo C, et al. Ondansetron and
droperidol in the prevention of postoperative nausea and
vomiting. Br J Anaesth 1999;83:813–4.
41. Pueyo FJ, Carrascosa F, Lopez L, Iribarren MJ, Garcia-
Pedrajas F, Saez A. Combination of ondansetron and
droperidol in the prophylaxis of postoperative nausea and
vomiting. Anesth Analg 1996;83:117–22.
42. Eberhart LHJ, Seeling W. Droperidol-supplemented
anaesthesia decreases post-operative nausea and vomiting but
impairs post-operative mood and well-being. Eur J Anaesth
1999;16:290–7.
43. Lim BSL, Pavy TJG, Lumsden G. The antiemetic and
dysphoric effects of droperidol in the day surgery patient.
Anaesth Intensive Care 1999;27:371–4.
44. Foster PN, Stickle BR, Laurence AS. Akathisia following low-
dose droperidol for antiemesis in day-case patients. Anaesthesia
1996;51:491–4.
45. Henzi I, Walder B, Tramer MR. Metoclopramide in the
prevention of postoperative nausea and vomiting: a quantitative
systematic review of randomized, placebo-controlled studies. Br
J Anaesth 1999;83:761–71.
2
3
3
3
1
999;54:266–71.
2. Fujii Y, Toyooka H, Tanaka H. Prophylactic anti-emetic therapy
with granisetron, droperidol and metoclopramide in female
patients undergoing middle ear surgery. Anaesthesia
1
998;53:1165–8.