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11. Sureshan, K. M.; Watanabe, Y. Synlett 2004, 493–
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References and notes
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13. 1H NMR (CDCl3, 400MHz): 1.34 (s, 3H); 1.48 (s, 3H);
1.49 (s, 3H); 1.50 (s, 3H); 3.84 (m, H-4); 3.88–3.94 (m, H-2
and H-3); 4.06 (t, 5.9Hz, H-5); 4.18 (dd, 5.40Hz, 1.95Hz,
H-6); 4.44 (t, 2.0Hz, H-1). 13C NMR (CDCl3, 100MHz):
25.5, 26.0, 26.9, 27.6, 56.9, 75.3, 75.5, 76.2, 77.6, 80.8,
109.7, 112.3. FABMS (M+1): 286.
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NMR (D2O, 100MHz): 64.5, 70.0, 70.1, 70.2, 72.6, 72.8.
15. 1H NMR (D2O, 400MHz): 3.36 (br, H-1); 3.55–3.65 (m,
2H, H-3 and H-4); 3.75–3.85 (br, H-5); 3.85–3.90 (br, H-
2); 4.05 (br, H-6). 13C NMR (D2O, 100MHz): 54.4, 70.0,
70.2, 71.9, 72.4, 72.8.
16. 1H NMR (CDCl3, 400MHz): 1.37 (s, 3H); 1.50 (s, 6H);
1.61 (s, 3H); 3.95 (dd, 10.0Hz, 2.8Hz, H-1); 4.15 (dd,
5.4Hz, 1.6Hz, H-4); 4.25 (dd, 5.4Hz, 2.8Hz, H-2); 4.29
(dd, 10.0Hz, 3.6Hz, H-6); 4.32 (t, 5.4Hz, H-3); 4.46 (dd,
3.6Hz, 1.6Hz, H-5). 13C NMR (CDCl3, 100MHz): 25.1,
25.2, 26.5, 26.7, 57.1, 60.5, 72.3, 72.5, 74.2, 77.3, 110.7,
112.2. Elemental analysis: calcd. for C12H18N6O4: C,
46.45; H, 5.85; N, 27.08. Found: C, 46.38; H, 5.81; N,
27.02.
17. 1H NMR (D2O, 400MHz, rt): 3.70–4.05 (br, 4H); 4.05–
4.25 (br, 2H). 1H NMR (D2O, 400MHz, 80°C): 3.80–3.86
(br, 1H); 3.88–3.98 (m, 2H); 4.03 (t, 1H); 4.12 (dd, 1H);
1
4.14–4.18 (m, 1H). H NMR (CD3OD, 400MHz): 3.45–
3.60 (br, 1H); 3.70–3.80 (m, 1H); 3.86 (dd, 9.70Hz,
3.08Hz, 1H); 3.95–4.00 (br, 1H); 4.00–4.05 (dd, 4.6Hz,
3.0Hz, 1H); 4.05–4.20 (br, 1H). 13C NMR (D2O,
100MHz, 80°C): 61.1, 62.2, 70.4, 70.7, 71.4, 72.0.
18. 1H NMR (D2O, 400MHz); 2.90 (br s, H-2); 2.98 (dd,
10.5Hz, 2.75Hz, H-5); 3.47 (dd, 10.5Hz, 1.3Hz, H-4); 3.74
(dd, 3.5Hz, 1.6Hz, H-1); 3.83 (dd, 1.3Hz, 2.5Hz, H-3);
3.89 (t, 3.50Hz, H-6). 13C NMR (D2O, 100MHz):
47.6, 47.7, 71.1, 72.0, 74.2, 74.3. FABMS (M+1): 179.
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