Journal of Heterocyclic Chemistry p. 1183 - 1188 (1984)
Update date:2022-08-11
Topics:
Lutz
McNamara
Olinger
et al.
5,6-Carbonyldioxyindole (4), a melanogenic derivative of 5,6-dihydroxyindole (1), was synthesized by a procedure starting with 3,4-methylenedioxycinnamic acid. Compound 4 is a stable crystalline solid which is readily hydrolyzed to 1, a key intermediate on the biosynthetic pathway from tyrosine to melanin.
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