Bioorganic and Medicinal Chemistry Letters p. 99 - 104 (1997)
Update date:2022-08-31
Topics:
Meier, Chris
Lorey, Martina
De Clercq
Balzarini, Jan
The synthesis of a new pro-nucleotide approach for d4TMP 2 based on cycloSal-4TMP 3a-d is described. Phosphotriesters 3 release d4TMP 2 selectively by a controlled, chemically induced tandem reaction. CycloSal-phosphotriesters 3 exhibited high biological activity against HIV-1/ HIV-2 in CEM cells which was retained in CEM TK- cells.
View MoreJiaozuo Zhongwen Trading Coporation Limited
Contact:+86 0391-3553810
Address:East Renmin Road
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
Contact:(1) 206-3550089
Address:5115 NE 8TH PL, Renton, WA 98059 USA
Contact:+49-4101-3053-0
Address:Waldhofstrasse 14 ,25474 Ellerbek Germany
Suzhou HeChuang Chemical Co.,Ltd.
Contact:+86-512-88800520
Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Doi:10.1002/chem.201804284
(2018)Doi:10.1016/S0040-4039(01)87919-3
(1969)Doi:10.1016/S0040-4020(01)81558-1
(1993)Doi:10.1021/acschembio.8b00257
(2018)Doi:10.1007/s11426-011-4398-4
(2011)Doi:10.1016/j.catcom.2015.01.031
(2015)