Tetrahedron Letters (2020)
Update date:2022-08-16
Topics:
Barker, David
Duhamel, Nina
Fedrizzi, Bruno
Jelley, Rebecca E.
A convenient, straightforward synthesis of the important amino acid-derived aroma precursors, 3-S-cysteinylhexan-1-ol (Cys-3SH) and 3-S-glutathionylhexan-1-ol (GSH-3SH) from commercially available butan-1-ol is reported. The versatility of this approach to include deuterium labelling is also demonstrated.
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