Communication
ChemComm
FRET signal between CPT and maleimide thioethers, suggesting 26 L. Liu, W. Wang, X.-J. Ju, R. Xie and L.-Y. Chu, Soft Matter, 2010, 6,
759–3763.
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the drug-release self-reporting properties of (CPT)
NPs. In vitro anticancer efficacy study demonstrated the GSH-
2
-Mal-PEG1k
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7 W. Wu, Q. Zhang, J. Wang, M. Chen, S. Li, Z. Lin and J. Li, Polym.
Chem., 2014, 5, 5668–5679.
responsive cancer inhibitory effect of (CPT) -Mal-PEG1k NPs. 28 R. Cheng, F. Feng, F. Meng, C. Deng, J. Feijen and Z. Zhong,
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J. Controlled Release, 2011, 152, 2–12.
Further studies of (CPT) -Mal-PEG NP, such as in vivo efficacy
and structural analysis, are underway.
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1k
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9 B. Khorsand, G. Lapointe, C. Brett and J. K. Oh, Biomacromolecules,
013, 14, 2103–2111.
This work was supported by the National Science Foundation 30 F. Meng, W. E. Hennink and Z. Zhong, Biomaterials, 2009, 30,
180–2198.
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(DMR-1309525) and the National Institutes of Health (NIH Director’s
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3
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