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1
Inspection of the H NMR spectra for samples of aqueous ICG stored
at room temperature for extended periods (Figure S19) showed that
the combined mass balance of ICG and 1 was >95% of the dye-
derived species. Mass spectral analysis of the samples indicated that
the remaining mass balance was a mixture of the other compounds
shown in Scheme 2, namely, the carbonyl-containing compounds and
truncated pentamethine homologue. The latter compound was
isolated and exhibited NMR and mass spectra that matched the
literature (Figure S25).
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