Brief Article
Journal of Medicinal Chemistry, 2009, Vol. 52, No. 14 4537
L337H rat nNOS. This material is available free of charge via
the Internet at http://pubs.acs.org.
Inhibitory effects of a series of 7-substituted-indazoles toward
nitric oxide synthases: particular potency of 1H-indazole-7-carbo-
nitrile. Bioorg. Med. Chem. 2008, 16, 5962–5973.
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18) Seo, J.; Igarashi, J.; Li, H.; Mart ꢀa sek, P.; Roman, L. J.; Poulos,
T. L.; Silverman, R. B. Structure-based design and synthesis of
N -nitro-L-arginine-containing peptidomimetics as selective inhi-
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structural water. J. Med. Chem. 2007, 50, 2089–2099.
19) Zhang, J.; Mart ꢀa sek, P.; Paschke, R.; Shea, T.; Masters, B. S. S.;
Kim, J.-J. P. Crystal structure of the FAD/NADPH-binding
domain of rat neuronal nitric-oxide synthase. Comparison with
NADPH-cytochrome P450 oxidoreductase. J. Biol. Chem. 2001,
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