Neurosci. Lett. 342 (2003) 13-16.
[5]
X. Xie, H. Yu, Y. Wang, Y. Zhou, G. Li, Z. Ruan, F. Li, X. Wang, H. Liu, J. Zhang,
Nicotinamide N-methyltransferase enhances the capacity of tumorigenesis associated with
the promotion of cell cycle progression in human colorectal cancer cells, Arch. Biochem.
Biophys. 564 (2014) 52-66.
[6]
[7]
[8]
J.M. Markert, C.M. Fuller, G.Y. Gillespie, J.K. Bubien, L.A. McLean, R.L. Hong, K. Lee,
S.R. Gullans, T.B. Mapstone, D.J. Benos, Differential gene expression profiling in human
brain tumors, Physiol. Genomics. 5 (2001) 21-33.
J. Xu, F. Moatamed, J.S. Caldwell, J.R. Walker, Z. Kraiem, K. Taki, G.A. Brent, J.M.
Hershman, Enhanced expression of nicotinamide N-methyltransferase in human papillary
thyroid carcinoma cells, J. Clin. Endocrinol. Metab. 88 (2003) 4990-4996.
M. Roessler, W. Rollinger, S. Palme, M.L. Hagmann, P. Berndt, A.M. Engel, B.
Schneidinger, M. Pfeffer, H. Andres, J. Karl, H. Bodenmüller, J. Rüschoff, T. Henkel, G.
Rohr, S. Rossol, W. Rösch, H. Langen, W. Zolg, M. Tacke, Identification of nicotinamide
N-methyltransferase as a novel serum tumor marker for colorectal cancer, Clin. Cancer
Res. 11 (2005) 6550-6557.
[9]
C. Brenner, Targeting a fat-accumulation gene, Nature. 508 (2014) 194-195.
[10] T.B. Domagala, A. Szeffler, L.W. Dobrucki, J. Dropinski, S. Polanski, M. Leszczynska-
Wiloch, K. Kotula-Horowitz, J. Wojciechowski, L. Wojnowski, A. Szczeklik, L.
Kalinowski, Nitric oxide production and endothelium-dependent vasorelaxation
ameliorated by N1-methylnicotinamide in human blood vessels, Hypertension. 59 (2012)
825-832.
[11] V. Pozzi, D. Sartini, S. Morganti, R. Giuliante, G. Di Ruscio, A. Santarelli, R. Rocchetti,
C. Rubini, M. Tomasetti, G. Giannatempo, F. Orlando, M. Provinciali, L. Lo Muzio, M.
Emanuelli, RNA-Mediated gene silencing of nicotinamide N-methyltransferase is
associated with decreased tumorigenicity in human oral carcinoma cells, PLoS One. 8
(2013) e71272.
[12] Y. Gao, M.J. Van Haren, E.E. Moret, J.J.M. Rood, D. Sartini, A. Salvucci, M. Emanuelli,
P. Craveur, N. Babault, J. Jin, N.I. Martin, Bisubstrate inhibitors of nicotinamide N-
methyltransferase (NNMT) with enhanced activity, J. Med. Chem. 62 (2019) 6597-6614.
[13] D. Chen, L. Li, K. Diaz, I.D. Iyamu, R. Yadav, N. Noinaj, R. Huang, Novel propargyl-
linked bisubstrate analogues as tight-binding inhibitors for nicotinamide N-
methyltransferase, J. Med. Chem. 62 (2019) 10783-10797.
[14] R.L. Policarpo, L. Decultot, E. May, P. Kuzmič, S. Carlson, D. Huang, V. Chu, B.A.
Wright, S. Dhakshinamoorthy, A. Kannt, S. Rani, S. Dittakavi, J.D. Panarese, R. Gaudet,
M.D. Shair, High-affinity alkynyl bisubstrate inhibitors of nicotinamide N-
methyltransferase (NNMT), J. Med. Chem. 62 (2019) 9837-9873.
[15] H. Neelakantan, H.Y. Wang, V. Vance, J.D. Hommel, S.F. McHardy, S.J. Watowich,
Structure-Activity Relationship for small molecule inhibitors of nicotinamide N-
methyltransferase, J. Med. Chem. 60 (2017) 5015-5028.
[16] A. Kannt, S. Rajagopal, S.V. Kadnur, J. Suresh, R.K. Bhamidipati, S. Swaminathan, M.S.
Hallur, R. Kristam, R. Elvert, J. Czech, A. Pfenninger, C. Rudolph, H. Schreuder, D.V.
Chandrasekar, V.S. Mane, S. Birudukota, S. Shaik, B.R. Zope, R.R. Burri, N.N. Anand,
M.K. Thakur, M. Singh, R. Parveen, S. Kandan, R. Mullangi, T. Yura, R. Gosu, S. Ruf, S.
Dhakshinamoorthy, A small molecule inhibitor of nicotinamide N-methyltransferase for
the treatment of metabolic disorders, Sci. Rep. 8 (2018) 3660.