Synthetic Communications p. 3685 - 3691 (2000)
Update date:2022-08-16
Topics:
Mignani
Mouysset
Le Roy
Stella
The reaction of chloroacetyl chloride and triethylamine with a chiral imine derived from the combination of methyl glyoxylate and protected L-threonine gave two optically active α-amino acid derivatives with a cis-substituted β-lactam skeleton in a 72:28 ratio. The major product is obtained in 59% yield by simple crystallisation.
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Doi:10.1007/s10562-010-0423-z
(2010)Doi:10.1016/S0022-2860(00)00847-4
(2001)Doi:10.1021/acs.joc.1c00379
(2021)Doi:10.1039/c3ra00134b
(2013)Doi:10.1073/pnas.1011499107
(2010)Doi:10.1016/S0040-4039(00)88445-2
(1982)