Journal of Medicinal Chemistry p. 8723 - 8733 (2015)
Update date:2022-08-11
Topics:
Kurbanov, Elbek K.
Chiu, Ting-Lan
Solberg, Jonathan
Francis, Subhashree
Maize, Kimberly M.
Fernandez, Jenna
Johnson, Rodney L.
Hawkinson, Jon E.
Walters, Michael A.
Finzel, Barry C.
Amin, Elizabeth Ambrose
The lethal factor (LF) enzyme secreted by Bacillus anthracis is a zinc hydrolase that is chiefly responsible for anthrax-related cell death. Although many studies of the design of small molecule LF inhibitors have been conducted, no LF inhibitor is yet av
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