LIQUID-PHASE HETEROGENEOUS OXIDATION OF HYDROXYPIVALALDEHYDE
945
is confirmed by the experimental dependence (7).
The features of HPA oxidation with oxygen in the
presence of 4% Pd/Al2O3 suggest that the kinetics
of D-glucose oxidation under similar conditions will
be similar. The process will also occur in two steps.
In the first step, formation of D-gluconic acid is possi-
ble, which will be further oxidized to D-glucaric acid.
4. Blyumberg, E.A. and Norikov, Yu.D., Itogi Nauki
Tekh., Ser: Kient. Katal., 1984, vol. 12, pp. 103 109.
5. Fel’dman, D.P., Voitenko, A.D., Shimanskaya, M.V.,
et al., Khim.-Farm. Zh., 1984, vol. 18, no. 11,
pp. 1356 1360.
6. Borovko, N.A., Chernaya, S.S., and Trusov, S.R.,
Zh. Prikl. Khim., 1999, vol. 72, no. 11, pp. 1842 1846.
7. Fel’dman, D.P., Voitenko, A.D., Shimanskaya, M.V.,
et al., Khim.-Farm. Zh., 1983, vol. 17, no. 2,
pp. 61 68.
CONCLUSIONS
(1) A kinetic study of liquid-phase oxidation of
hydroxypivalaldehyde with molecular oxygen in the
presence of a heterogeneous catalyst, 4% Pd/Al2O3,
showed that the oxidation occurs in two steps. Hy-
droxypivalic acid formed in the first step is oxidized
to dimethylmalonic acid in the second step.
8. Hiroshi, K., Akio, K., Isao, K., et al., Appl. Catal.
A: General, 1993, vol. 95, no. 2, pp. 143 169.
9. Mitsuo, A., Shinji, N., Toshiyuki, S., et al., Bull.
Chem. Soc. Jpn., 1993, vol. 66, no. 5, pp. 1511 1515.
10. Shlangen, I.W.A., Neuhaus, G.W., Mandani, M.,
et al., Allgem. Praktt. Chem., 1992, vol. 334, no. 6,
pp. 465 473.
11. Adler, Yu.P., Markova, E.V., and Granovskii, Yu.V.,
Planirovanie eksperimenta pri poiske optimal’mykh
uslovii (Experimental Design in Searching for Optimal
Conditions), Moscow: Nauka, 1976.
(2) A kinetic equation of hydroxypivalaldehyde
oxidation to hydroxypivalic acid was derived. The
activation energy of this process was determined.
REFERENCES
12. Norikov, Yu.D., Blyumberg, E.A., Bochorshvili, Sh.K.,
et al., Dokl. Akad. Nauk SSSR, 1975, vol. 223, no. 5,
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1. Grigor’eva, I.A., Chernaya, S.S., Trusov, S.R., et al.,
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RUSSIAN JOURNAL OF APPLIED CHEMISTRY Vol. 75 No. 6 2002