Journal of the American Chemical Society
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Ofek, I.; Cohen, S.; Rahmani, R.; Kabha, K.; Tamarkin, D.;
Funding Sources
Herzig, Y.; Rubinstein, E., Antimicrob. Agents Ch. 1994, 38, 374.
11.
(a) May, J. M.; Owens, T. W.; Mandler, M. D.; Simpson,
ACKNOWLEDGMENT
B. W.; Lazarus, M. B.; Sherman, D. J.; Davis, R. M.; Okuda, S.;
Massefski, W.; Ruiz, N.; Kahne, D., J. Am. Chem. Soc. 2017, 139,
17221; (b) Sherman, D. J.; Lazarus, M. B.; Murphy, L.; Liu, C.;
Walker, S.; Ruiz, N.; Kahne, D., Proc. Natl. Acad. Sci. USA 2014,
111, 4982; (c) Sperandeo, P.; Cescutti, R.; Villa, R.; Di Benedetto, C.;
Candia, D.; Deho, G.; Polissi, A., J. Bacteriol. 2007, 189, 244.
This research was supported by the NIH (R01 GM066174, U19
AI109764, and R01 AI081059 to D.K.; F31GM116210 to J.L.),
NSF GRFP (DGEꢀ1144152 to M.D.M.), and the Blavatnik Bioꢀ
medical Accelerator at Harvard University. We wish to thank the
Dana Farber Cancer Institute / Harvard Medical School joint
NMR Core. We thank Dr. ShaoꢀLiang Zheng for his help with the
Xꢀray data collection and structure determination for 3.
12.
(a) Okuda, S.; Freinkman, E.; Kahne, D., Science 2012,
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338, 1214; (b) Narita, S.; Tokuda, H., FEBS Lett. 2009, 583, 2160; (c)
Sperandeo, P.; Lau, F. K.; Carpentieri, A.; De Castro, C.; Molinaro,
A.; Deho, G.; Silhavy, T. J.; Polissi, A., J. Bacteriol. 2008, 190, 4460.
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14.
2309.
15.
e107289.
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carbapenemꢀresistant Enterobacteriaceae, Acinetobacter baumannii
and Pseudomonas aeruginosa in health care facilities. World Health
Organization: Geneva, 2017; (b) Willyard, C., Nature 2017, 543, 15.
17.
M.; May, J. M.; Trauger, S. A.; Kahne, D.; Ruiz, N., MBio 2016, 7, 1.
18. Tran, A. X.; Trent, M. S.; Whitfield, C., J. Biol. Chem.
2008, 283, 20342.
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