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SHAABANI ET AL.
slowly to the reaction mixture and the solution was
stirred for 30 min at 90 °C. Next, H O (25 ml of a 30%
ACKNOWLEDGEMENTS
2
2
We gratefully acknowledge financial support of the Iran
National Science Foundation (INSF) and the Research
Council of Shahid Beheshti University.
solution) and deionized water (25 ml) were added to the
mixture. Then resulting precipitate was centrifuged and
washed repeatedly with HCl (5%, 3 × 15 ml) and EtOH
and vacuum dried at 60 °C. The GO was obtained as a
brown powder.
CONFLICTS OF INTEREST
There are no conflicts to declare.
2.5 | Preparation of GO‐vitamin B12
ORCID
Initially, vitamin B12 (Cyanocobalamin derivative)
100 mg) was added to a 5 ml EtOH in a flask and thor-
(
oughly stirred. After dissolving the vitamin B12 in EtOH,
GO powder (1.00 g) was added to the above solution
and obtained mixture was sonicated for 30 minutes.
Then, the solution was stirred for 24 h at room tempera-
ture. Afterwards, the resulted mixture was subjected to
centrifugation and thoroughly washed with EtOH for at
least five times. The product was carefully collected and
dried under vacuum until constant weight.
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of alcohols
A mixture of an alcohol (1.00 mmol), KOH (0.50 mmol),
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two‐necked vial containing o‐xylene (5 ml) as solvent
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3
| CONCLUSIONS
In summary, we have successfully developed graphene
oxide functionalized with vitamin B12 as a green and
reusable catalyst and for the first time we have demon-
strated that vitamin B12 efficiently catalyze the aerobic
oxidation of a wide range of primary and secondary
alcohols in to the corresponding aldehydes or ketones
under optimal and environmentally‐friendly reaction
conditions with high conversions. Moreover, in view of
the simplicity and non‐hazardous nature of the catalyst
and commercial availability of vitamin B12 from natural
resources and industrial fermentation at relatively low
costs, it might be a useful catalyst for the variety of
experiments.
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