Phytochemistry p. 332 - 334 (1980)
Update date:2022-08-29
Topics:
Ghosal, Shibnath
Banerjee, Shanta
Jaiswal, Dinesh K.
A new 3,7-dioxabicyclo<3,3,0>octane lignan, named justisolin, and a new lignan O-glucoside, named simplexoside, were isolated from the whole plant of justicia simplex D.Don. (Acanthaceae), collected at fruiting.The structure of the free lignan was established as 2e-(3,4-methylenedioxy-6-hydroxy)-phenyl-6e-piperonyl-3,7-dioxabicyclo<3,3,0>octane (1) and that of the glucoside as 2e-(3-methoxy-4-O-β-D-glucopyranosyl)-phenyl-6e-piperonyl-3,7-dioxabicyclo<3,3,0>octane (2) on the basis of chemical transformation and spectral evidence.The biological functions of these and related lignans are appraised.Key Word Index - Justicia simplex; Acanthaceae; 3,7-dioxabicyclo<3,3,0>octane lignan; justisolin; lignan O-glucoside; simplexoside; isolation; structure elucidation; biological function.
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