Natural Product Research p. 2964 - 2970 (2020)
Update date:2022-08-17
Topics:
Huu Tai, Bui
Xuan Nhiem, Nguyen
Hai Yen, Pham
Hong Quang, Tran
Thi Cuc, Nguyen
Thi Trang, Do
Van Doan, Vu
Thuy Hang, Dan Thi
Van Minh, Chau
Van Kiem, Phan
Three new muurolane type sesquiterpene glycosides, named balanoindicosides A ? C (1 ? 3), were isolated from the whole plant of Balanophora fungosa subsp. indica using various chromatographic methods. Their structures were determined by extensive analysis of HR-ESI-MS and NMR spectroscopy. The stereochemistry of muurolane sesquiterpene backbone was demonstrated by NOESY analysis. Configuration of C-12 in compounds 2 and 3 could be distinguished by chemical shift value of C-14. Compounds 1-3 exhibited weak cytotoxic activity towards HepG-2, HL-60, LU-1, and MCF-7 cell lines.
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