Synthetic Communications p. 4195 - 4209 (1996)
Update date:2022-08-10
Topics:
Bright, Robert
Coote, Steven J.
Freeman, Stephen
Hayes, Doug
Smith, Gordon
Tapolczay, David
5-Bromobarbituric acid (5) is a convenient reagent for the selective bromination of cyclic imine 3. A facile, in situ synthesis of this reagent involving a disproportionation reaction between barbituric acid and dibromobarbituric acid is described.
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