Steroids (2021)
Update date:2022-08-11
Topics:
Xia, Xi
Chen, Yu
Wang, Lin
Yang, Zhi-Gang
Ma, Xiao-Dong
Zhao, Zhi-Gang
Yang, Hong-Jun
Giosgenin is a naturally steroidal saponin exhibiting a variety of biological activities including antitumor ones. A series of novel diosgenyl quaternary ammonium derivatives were designed and synthesized to develop potential anti-tumor agents in our research. All novel derivatives were characterized by 1H NMR, 13C NMR and HR-MS, and evaluated for their in vitro anti-proliferative activities using MTT assay. The human cancer cell lines were A549 (Human lung cancer cell), H1975 (Human lung adenocarcinoma cell), A431 (Human skin squamous cell carcinoma), HCT-116 (Human colorectal adenocarcinoma cell), Aspc-1 (Human metastatic pancreatic cancer cell), Ramos (Human B lymphoma cell), HBE (Human bronchial epithelioid cell) and LO2 (Human normal hepatocyte).
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Doi:10.1021/jo00122a041
(1995)Doi:10.1007/BF02494670
(2000)Doi:10.1055/s-1976-24159
(1976)Doi:10.1016/j.electacta.2005.03.046
(2005)Doi:10.1063/1.117191
(1996)Doi:10.1016/j.procbio.2014.06.016
(2014)