Journal of Asian Natural Products Research p. 604 - 610 (2011)
Update date:2022-08-11
Topics:
Bai, Xue
Qu, Jia-Lin
Liu, Jia
Sun, Jia-Hong
Yuan, Dan
Tectoridin is an active isoflavone from the rhizome of Belamcanda chinensis and flower of Pueraria thomsonii Benth, possessing an anti-inflammation action and the protective effect against ethanol-induced intoxication and hepatic injury. The metabolism of tectoridin was investigated in rats. Nine metabolites were isolated by using repeated chromatographic methods and identified by spectroscopic methods including UV, IR, mass spectrometry, and NMR experiments. A new compound was determined as tectorigenin-7-O-β-D-glucuronide (M-1), together with eight known compounds identified as irisolidone-7-O-β-D- glucuronide (M-2), tectorigenin-7-O-sulfate (M-3), tectorigenin-4′-O- sulfate (M-4), tectorigenin (M-5), irisolidone (M-6), isotectorigenin (M-7), genistein (M-8), and daidzein (M-9), respectively. The metabolic pathway of tectoridin was proposed, which is important to understand its metabolic fate and disposition in humans.
View MoreAstaTech ( Chengdu) BioPharmaceutical Corp.
website:http://www.astabiochem.cn/
Contact:+86-15680585308
Address:SICHUAN CHENGDU
Shanghai Synmedia Chemical Co., Ltd
Contact:+86-21-38681880
Address:6th Floor, 11A Building, No.528 Ruiqing Road, Heqing town, Pudong new district, Shanghai China
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Qingdao XinYongAn Chemicals Co., Ltd
Contact:+86-532-81107967
Address:Chengyang dual-port industrial park by the sea,Qingdao
Yangzhou Zhongbao Pharmaceutical Co.,Ltd
Contact:+86-514-88290838
Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Doi:10.1007/BF02755373
(2000)Doi:10.1063/1.1509096
(2002)Doi:10.1007/BF02496340
(2000)Doi:10.1021/jacs.0c09015
(2021)Doi:10.1055/s-0035-1561200
(2016)Doi:10.1002/chem.201406281
(2015)