Tetrahedron Asymmetry p. 2395 - 2402 (1995)
Update date:2022-08-17
Topics:
Tungler
Mathe
Tarnai
Fodor
Toth
Kajtar
Kolossvary
Herenyi
Sheldon
The preparation, characterisation and use of (-)-dihydro-apovincaminic acid ethyl ester as a chiral modifier in heterogeneous catalytic asymmetric hydrogenations is reported. The epimeric compositions were determined using NMR and HPLC methods and circular dichroism spectroscopy was used to detect the interaction between the chiral modifier and the substrate.
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