Journal of Heterocyclic Chemistry p. 917 - 922 (1989)
Update date:2022-08-16
Topics:
Guiotto
Chilin
Pastorini
A number of methylfuro[3,2-g]quinolin-7(8H)-ones, which can be considered isosters of methylpsoralens, were synthesized. The synthesis was performed starting from the appropriate methyl quinolin-2-ones on which the methylfuran ring was condensed. The molar absorptivity at long wavelengths of these compounds is remarkably higher than that of the corresponding methylpsoralen isosters; this fact may lead to an improved photo-binding to the biological targets.
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