Journal of Pharmaceutical Sciences p. 362 - 364 (1982)
Update date:2022-08-11
Topics:
Graham
Dejuliis
Mattson
Sowell Sr.
The synthesis and biodistribution properties of 99mTc-labeled 5-substituted N-(3-cyano-4-methyl-2-pyrrylcarbamoylmethyl)iminodiacetic acids and a similar series of N1-methyl analogs are described. These compounds were compared with 99mTc-labeled N-(2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid for hepatobiliary activity in the rat. The effects of structural modifications on biological activity are also reported.
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