Journal of Agricultural and Food Chemistry
ARTICLE
(6) Roldan, A.; Palacios, V.; Caro, I.; Perez, L. Evolution of Resver-
atrol and Piceid Contents during the Industrial Winemaking Process of
Sherry Wine. J. Agric. Food Chem. 2010, 58 (7), 4268–4273.
(7) Tokusoglu, O.; Unal, M. K.; Yemis, F. Determination of the
phytoalexin resveratrol (3,5,40-trihydroxystilbene) in peanuts and pis-
tachios by high-performance liquid chromatographic diode array
(HPLC-DAD) and gas chromatography-mass Spectrometry (GC-
MS). J. Agric. Food Chem. 2005, 53 (12), 5003–5009.
(8) Lopez-Hernandez, J.; Paseiro-Losada, P.; Sanches-Silva, A. T.;
Lage-Yusty, M. A. Study of the changes of trans-resveratrol caused by
ultraviolet light and determination of trans- and cis-resveratrol in Spanish
white wines. Eur. Food Res. Technol. 2007, 225 (5-6), 789–796.
(9) Stervbo, U.; Vang, O.; Bonnesen, C. A review of the content of
the putative chemopreventive phytoalexin resveratrol in red wine. Food
Chem. 2007, 101 (2), 449–457.
(10) Renaud, S.; Delorgeril, M. Wine, Alcohol, Platelets, and the
French Paradox for Coronary Heart-Disease. Lancet 1992, 339 (8808),
1523–1526.
(11) Athar, M.; Back, J. H.; Tang, X.; Kim, K. H.; Kopelovich, L.;
Bickers, D. R.; Kim, A. L. Resveratrol: a review of preclinical studies
for human cancer prevention. Toxicol. Appl. Pharmacol. 2007, 224 (3),
274–83.
and grape seed capsules with automated solid phase extraction. J. Liq.
Chromatogr. Relat. Technol. 2000, 23 (10), 1555–1564.
(25) Dominguez, C.; Guillen, D. A.; Barroso, C. G. Automated solid-
phase extraction for sample preparation followed by high-performance
liquid chromatography with diode array and mass spectrometric detec-
tion for the analysis of resveratrol derivatives in wine. J. Chromatogr., A
2001, 918 (2), 303–310.
(26) Urpi-Sarda, M.; Zamora-Ros, R.; Lamuela-Raventos, R.; Cher-
ubini, A.; Jauregui, O.; De la Torre, R.; Covas, M. I.; Estruch, R.; Jaeger,
W.; Andres-Lacueva, C. HPLC-tandem mass spectrometric method to
characterize resveratrol metabolism in humans. Clin. Chem. 2007, 53
(2), 292–299.
(27) Vlase, L.; Kiss, B.; Leucuta, S. E.; Gocan, S.; Rapid, A Method
for Determination of Resveratrol in Wines by HPLC-MS. J. Liq.
Chromatogr. Relat. Technol. 2009, 32 (14), 2105–2121.
(28) Vinas, P.; Campillo, N.; Martinez-Castillo, N.; Hernandez-
Cordoba, M. Solid-phase microextraction on-fiber derivatization for
the analysis of some polyphenols in wine and grapes using gas
chromatography-mass spectrometry. J. Chromatogr., A 2009, 1216 (9),
1279–1284.
(29) Peres, R. G.; Micke, G. A.; Tavares, M. F. M.; Rodriguez-
Amaya, D. B. Multivariant optimization, validation, and application
of capillary electrophoresis for simultaneous determination of polyphe-
nols and phenolic acids in Brazilian wines. J. Sep. Sci. 2009, 32 (21),
3822–3828.
(12) Baur, J. A.; Sinclair, D. A. Therapeutic potential of resveratrol:
the in vivo evidence. Nat. Rev. Drug Discovery 2006, 5 (6), 493–506.
(13) Jang, M.; Cai, L.; Udeani, G. O.; Slowing, K. V.; Thomas, C. F.;
Beecher, C. W.; Fong, H. H.; Farnsworth, N. R.; Kinghorn, A. D.; Mehta,
R. G.; Moon, R. C.; Pezzuto, J. M. Cancer chemopreventive activity of
resveratrol, a natural product derived from grapes. Science 1997, 275
(5297), 218–220.
(30) Gu, X. L.; Chub, Q. Y.; O’Dwyer, M.; Zeece, M. Analysis of
resveratrol in wine by capillary electrophoresis. J. Chromatogr., A 2000,
881 (1-2), 471–481.
(31) Feijoo, O.; Moreno, A.; Falque, E. Content of trans- and cis-
resveratrol in Galician white and red wines. J. Food Compos. Anal. 2008,
21 (8), 608–613.
(14) Aggarwal, B; Shishodia, S. Resveratrol in health and disease; CRC
Press: Boca Raton, 2006.
(15) Paulo, L.; Ferreira, S.; Gallardo, E.; Queiroz, J. A.; Domingues,
F. Antimicrobial activity and effects of resveratrol on human pathogenic
bacteria. World J. Microbiol. Biotechnol. 2010, 26 (8), 1533–1538.
(16) Bertelli, A. A. A.; Das, D. K. Grapes, Wines, Resveratrol, and
Heart Health. J. Cardiovasc. Pharmacol. 2009, 54 (6), 468–476.
(17) Babu, S. K.; Kumar, K. V.; Subbaraju, G. V. Estimation of trans-
resveratrol in herbal extracts and dosage forms by high-performance
thin-layer chromatography. Chem. Pharm. Bull. (Tokyo) 2005, 53 (6),
691–693.
(18) Vian, M. A.; Tomao, V.; Gallet, S.; Coulomb, P. O.; Lacombe,
J. M. Simple and rapid method for cis- and trans-resveratrol and piceid
isomers determination in wine by high-performance liquid chromatog-
raphy using Chromolith columns. J. Chromatogr., A 2005, 1085 (2),
224–229.
(19) Rodriguez-Delgado, M. A.; Malovana, S.; Perez, J. P.; Borges,
T.; Montelongo, F. J. G. Separation of phenolic compounds by high-
performance liquid chromatography with absorbance and fluorimetric
detection. J. Chromatogr., A 2001, 912 (2), 249–257.
(20) Tarola, A. M.; Milano, F.; Giannetti, V. Simultaneous determi-
nation of phenolic compounds in red wines by HPLC-UV. Anal. Lett.
2007, 40 (12), 2433–2445.
(21) La Torre, G. L.; Saitta, M.; Vilasi, F.; Pellicano, T.; Dugo, G.
Direct determination of phenolic compounds in Sicilian wines by liquid
chromatography with PDA and MS detection. Food Chem. 2006, 94 (4),
640–650.
(22) Sanchez, J. B. J.; Corral, E. C.; Delgado, M. J. S.; Orea, J. M.;
Urena, A. G. Analysis of trans-resveratrol by laser ionization mass
spectrometry and HPLC with fluorescence detection - Comparison
between both techniques. J. Chromatogr., A 2005, 1074 (1-2), 133–138.
(23) de Quiros, A. R. B.; Lopez-Hernandez, J.; Ferraces-Casais, P.;
Lage-Yusty, M. A. Analysis of non-anthocyanin phenolic compounds
in wine samples using high performance liquid chromatography
with ultraviolet and fluorescence detection. J. Sep. Sci. 2007, 30 (9),
1262–1266.
(32) Diaz, T. G.; Meras, I. D.; Rodriguez, D. A. Determination of
resveratrol in wine by photochemically induced second-derivative
fluorescence coupled with liquid-liquid extraction. Anal. Bioanal. Chem.
2007, 387 (6), 1999–2007.
(33) Bravo, M. N.; Feliciano, R.; Silva, S.; Coelho, A. V.; Boas, L. V.;
Bronze, M. R. Analysis of trans-resveratrol: Comparison of methods and
contents in Muscatel fortified wines from Setubal region in Portugal.
J. Food Compos. Anal. 2008, 21 (8), 634–643.
(34) Nave, F.; Cabrita, M. J.; da Costa, C. T. Use of solid-supported
liquid-liquid extraction in the analysis of polyphenols in wine.
J. Chromatogr., A 2007, 1169 (1-2), 23–30.
(35) Gerogiannaki-Christopoulou, M.; Athanasopoulos, P.; Kyriaki-
dis, N.; Gerogiannaki, I. A.; Spanos, M. trans-resveratrol in wines from
the major Greek red and white grape varieties. Food Control 2006, 17
(9), 700–706.
(36) Mercolini, L.; Saracino, M. A.; Bugamelli, F.; Ferranti, A.;
Malaguti, M.; Hrelia, S.; Raggi, M. A. HPLC-F analysis of melatonin
and resveratrol isomers in wine using an SPE procedure. J. Sep. Sci. 2008,
31 (6-7), 1007–1014.
(37) Baptista, J. A. B.; Tavares, J. F. D.; Carvalho, R. C. B. Compar-
ison of polyphenols and aroma in red wines from Portuguese mainland
versus Azores Islands. Food Res. Int. 2001, 34 (4), 345–355.
(38) Gamoh, K.; Nakashima, K. Liquid chromatography/mass spec-
trometric determination of trans-resveratrol in wine using a tandem
solid-phase extraction method. Rapid Commun. Mass Spectrom. 1999, 13
(12), 1112–1115.
(39) Vinas, P.; Campillo, N.; Hernandez-Perez, M.; Hernandez-
Cordoba, M. A comparison of solid-phase microextraction and stir bar
sorptive extraction coupled to liquid chromatography for the rapid
analysis of resveratrol isomers in wines, musts and fruit juices. Anal.
Chim. Acta 2008, 611 (1), 119–125.
(40) Katsagonis, A.; Atta-Politou, J.; Koupparis, M. A. HPLC
method with UV detection for the determination of trans-resveratrol
in plasma. J. Liq. Chromatogr. Relat. Technol. 2005, 28 (9), 1393–1405.
(41) Trela, B. C.; Waterhouse, A. L. Resveratrol: isomeric molar
absorptivities and stability. J. Agric. Food Chem. 1996, 44 (5),
1253–1257.
(24) Zhu, Y. X.; Coury, L. A.; Long, H.; Duda, C. T.; Kissinger, C. B.;
Kissinger, P. T. Liquid chromatography with multichannel electroche-
mical detection for the determination of resveratrol in wine, grape juice,
2167
dx.doi.org/10.1021/jf105004y |J. Agric. Food Chem. 2011, 59, 2157–2168