Chemistry of Heterocyclic Compounds p. 95 - 99 (1983)
Update date:2022-08-11
Topics:
Upadysheva, A. V.
Grigor'eva, N. D.
Ryabokobylko, Yu. S.
Znamenskaya, A. P.
The intramolecular cationotropic rearrangement of salts of two-ring 2,2-disubstituted 4-chloro-1,2-dihydropyrimidines to 4-aminopyrimidine derivatives was observed.Recyclization to 4-aminopyridines can take place in the reaction of two-ring 2,2-disubstituted 4(3H)-oxo-1,2-dihydropyrimidines with phosphorus oxychloride without isolation of the intermediate chloro derivatives.A probable mechanism that makes it possible to assert that the observed recyclization is a variant of the intramolecular cationotropic rearrangement that is characteristic for 2,2-dialkylsubstituted 1,2-dihydropyrimidines with functional substituents (for example, oxo or chloro) in the 4 position of the ring is discussed.
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Doi:10.1002/jlac.197519750508
(1975)Doi:10.1016/0304-4165(71)90210-8
(1971)Doi:10.1023/B:RUCO.0000022806.85114.93
(2004)Doi:10.1016/j.tetlet.2003.08.086
(2003)Doi:10.1039/c4ra04830j
(2014)Doi:10.1016/S0040-4020(97)00600-5
(1997)