Synthetic Communications p. 2775 - 2781 (1996)
Update date:2022-08-22
Topics:
Weidner-Wells, Michele A.
Fraga-Spano, Stephanie A.
An improved method for the synthesis of 3,5-difluorosalicylic acid (3b) and 3,5-difluorosalicylaldehyde (3a) is described. 2,4-Difluorophenol (4) undergoes a formylation reaction to afford aldehyde 3a which is oxidized to the desired acid 3b. This method
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Doi:10.1002/cplu.201200092
(2012)Doi:10.1016/j.poly.2013.04.016
(2013)Doi:10.1016/j.tetlet.2014.11.128
(2015)Doi:10.1081/SCC-120021044
(2003)Doi:10.1111/j.0014-3820.2003.tb00347.x
()Doi:10.1021/jacs.1c04288
(2021)