Tetrahedron p. 8771 - 8782 (1998)
Update date:2022-08-11
Topics:
Pasquinet, Eric
Rocca, Patrick
Marsais, Francis
Godard, Alain
Queguiner, Guy
2-Isopropylpyridine has been successfully metallated and functionalized by using potassium diisopropylamide (KDA). Subsequent functionalization has been achieved with a wide range of electrophiles and good to excellent yields have been obtained. The action of other potassium or sodium bases has also been investigated.
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