10.1002/anie.201915100
Angewandte Chemie International Edition
RESEARCH ARTICLE
J. Am. Chem. Soc. 2013, 135, 12180-12183; c) H. B. Qiu, Z. M. Hudson,
M. A. Winnik, I. Manners, Science 2015, 347, 1329-1332; d) X. M. He, M.
S. Hsiao, C. E. Boott, R. L. Harniman, A. Nazemi, X. Y. Li, M. A. Winnik,
I. Manners, Nat. Mater. 2017, 16, 481-488.
Conclusion
[7]
[8]
J. C. Foster, S. Varlas, B. Couturaud, Z. Coe, R. K. O'Rei'lly, J. Am.
Chem. Soc. 2019, 141, 2742-2753.
In summary, we have shown a versatile approach that
combines guided dewetting, transfer printing and laser-assisted
patterning techniques for the fabrication of new soft integrated
devices consisting of hydrogels and well-organized micellar
filaments. Owing to the characteristic of flexible shape design and
printing technique in our approach, two prototypes of soft devices,
fishnet-like soft cage and soft actuator, have been successfully
constructed. On the one hand, passive devices composed of
freely suspended micellar filaments attached to a hydrogel
framework are created and are used as a size-exclusion sieve
and cage. These micellar filaments can withstand a point bending
force of 2.73 pN at least, which is in the similar range of cellular
molecular mechanotransduction. Due to this high sensitivity of
their deflections (in the range of piconewton), these freely
suspended micellar filaments have potential as a tool for
molecular force measurements. On the other hand, a kind of soft
actuators, of which the rolling directionality is governed by the well
organized and embedded micelles, is created. Importantly, we
notice that a single layer of micellar filaments is capable of control
over the rolling direction, which might lead to the development of
soft actuators controlled with tiny amount of supramolecular
assemblies. It is expected that the presented strategy of
manipulation and integration of supramolecular assemblies may
open new doors for designing and manufacturing intelligent
biomaterials with enticing applications in a broad of fields, such
as responsive tissue engineering scaffolds and soft robots.
a) R. Glass, M. Moller, J. P. Spatz, Nanotechnology 2003, 14, 1153-
1160; b) B. Li, W. Han, B. B. Jiang, Z. Q. Lin, Acs Nano 2014, 8, 2936-
2942; c) D. Kiriya, M. Ikeda, H. Onoe, M. Takinoue, H. Komatsu, Y.
Shimoyama, I. Hamachi, S. Takeuchi, Angew. Chem. Int. Edit. 2012, 51,
1553-1557; d) S. M. Zhang, M. A. Greenfield, A. Mata, L. C. Palmer, R.
Bitton, J. R. Mantei, C. Aparicio, M. O. de la Cruz, S. I. Stupp, Nat. Mater.
2010, 9, 594-601.
[9]
X. D. Chen, S. Lenhert, M. Hirtz, N. Lu, H. Fuchs, L. F. Chi, Accounts
Chem. Res. 2007, 40, 393-401.
[10] a) P. van der Asdonk, H. C. Hendrikse, M. F. C. Romera, D. Voerman,
B. E. I. Ramakers, D. W. P. M. Lowik, R. P. Sijbesma, P. H. J. Kouwer,
Adv. Funct. Mater. 2016, 26, 2609-2616; b) P. van der Asdonk, P. H. J.
Kouwer, Chem. Soc. Rev. 2017, 46, 5935-5949.
[11] L. Sardone, V. Palermo, E. Devaux, D. Credgington, M. De Loos, G.
Marletta, F. Cacialli, J. Van Esch, P. Samori, Adv. Mater. 2006, 18, 1276-
1280.
[12] B. R. Cao, Y. Zhu, L. Wang, C. B. Mao, Angew. Chem. Int. Edit. 2013,
52, 11750-11754.
[13] T. Fukui, T. Uchihashi, N. Sasaki, H. Watanabe, M. Takeuchi, K.
Sugiyasu, Angew. Chem. Int. Edit. 2018, 57, 15465-15470.
[14] a) O. E. C. Gould, H. Qiu, D. J. Lunn, J. Rowden, R. L. Harniman, Z. M.
Hudson, M. A. Winnik, M. J. Miles, I. Manners, Nat. Commun. 2015, 6;
b) O. E. C. Gould, S. J. Box, C. E. Boott, A. D. Ward, M. A. Winnik, M. J.
Miles, I. Manners, ACS Nano 2019, 13, 3858-3866.
[15] a) P. J. Glazer, L. Bergen, L. Jennings, A. J. Houtepen, E. Mendes, P. E.
Boukany, Small 2014, 10, 1729-1734; b) K. Zhang, P. J. Glazer, L.
Jennings, S. Vedaraman, S. Oldenhof, Y. Wang, F. Schosseler, J. H. van
Esch, E. Mendes, Chem. Commun. 2016, 52, 12360-12363.
[16] B. D. Fairbanks, M. P. Schwartz, C. N. Bowman, K. S. Anseth,
Biomaterials 2009, 30, 6702-6707.
[17] a) J. H. Zhu, S. Y. Zhang, K. Zhang, X. J. Wang, J. W. Mays, K. L. Wooley,
D. J. Pochan, Nat. Commun. 2013, 4; b) K. Zhang, A. Suratkar, S.
Vedaraman, V. Lakshminarayanan, L. Jennings, P. J. Glazer, J. H. van
Esch, E. Mendes, Macromolecules 2018, 51, 5788-5797.
[18] A. Freikamp, A. L. Cost, C. Grashoff, Trends Cell Biol. 2016, 26, 838-
847.
[19] a) J. Kim, J. A. Hanna, M. Byun, C. D. Santangelo, R. C. Hayward,
Science 2012, 335, 1201-1205; b) Z. L. Wu, M. Moshe, J. Greener, H.
Therien-Aubin, Z. H. Nie, E. Sharon, E. Kumacheva, Nat. Commun. 2013,
4; c) A. S. Gladman, E. A. Matsumoto, R. G. Nuzzo, L. Mahadevan, J. A.
Lewis, Nat Mater 2016, 15, 413-418; d) Y. S. Zhang, A. Khademhosseini,
Science 2017, 356; e) S. J. Jeon, A. W. Hauser, R. C. Hayward, Accounts
Chem. Res. 2017, 50, 161-169; f) K. Sano, Y. Ishida, T. Aida, Angew.
Chem. Int. Edit. 2018, 57, 2532-2543.
Acknowledgements
The authors gratefully thank the China Scholarship Council (CSC)
for financial support.
[20] a) L. Ionov, Mater. Today 2014, 17, 494-503; b) X. X. Le, W. Lu, J. W.
Zhang, T. Chen, Adv. Sci. 2019, 6.
[21] D. Q. Liu, C. W. M. Bastiaansen, J. M. J. den Toonder, D. J. Broer, Soft
Keywords: block copolymers • micelles • hydrogels • transfer
Matter 2013, 9, 588-596.
printing, laser-assisted patterning
[22] a) P. Fratzl, R. Elbaum, I. Burgert, Faraday Discuss. 2008, 139, 275-282;
b) R. M. Erb, J. S. Sander, R. Grisch, A. R. Studart, Nat. Commun. 2013,
4.
[1]
[2]
a) G. M. Whitesides, B. Grzybowski, Science 2002, 295, 2418-2421; b)
J. M. Lehn, Science 2002, 295, 2400-2403; c) S. Mann, Nat. Mater. 2009,
8, 781-792; d) S. I. Stupp, L. C. Palmer, Chem. Mater. 2014, 26, 507-
518; e) D. Philp, J. F. Stoddart, Angew. Chem. Int. Edit. 1996, 35, 1155-
1196.
a) A. P. H. J. Schenning, E. W. Meijer, Chem. Commun. 2005, 3245-
3258; b) N. Tuccitto, V. Ferri, M. Cavazzini, S. Quici, G. Zhavnerko, A.
Licciardello, M. A. Rampi, Nat. Mater. 2009, 8, 41-46; c) M. Urdampilleta,
S. Klyatskaya, J. P. Cleuziou, M. Ruben, W. Wernsdorfer, Nat. Mater.
2011, 10, 502-506; d) L. Zhang, X. L. Zhong, E. Pavlica, S. L. Li, A.
Klekachev, G. Bratina, T. W. Ebbesen, E. Orgiu, P. Samori, Nat.
Nanotechnol. 2016, 11, 900-907.
[3]
a) A. R. Hirst, B. Escuder, J. F. Miravet, D. K. Smith, Angew. Chem. Int.
Edit. 2008, 47, 8002-8018; b) A. C. Mendes, E. T. Baran, R. L. Reis, H.
S. Azevedo, Wires Nanomed. Nanobi. 2013, 5, 582-612; c) S. G. Zhang,
Nat. Biotechnol. 2003, 21, 1171-1178; d) K. Kataoka, A. Harada, Y.
Nagasaki, Adv. Drug Deliver. Rev. 2001, 47, 113-131; e) H. Cabral, K.
Miyata, K. Osada, K. Kataoka, Chem. Rev. 2018, 118, 6844-6892.
a) J. Schobel, M. Burgard, C. Hils, R. Dersch, M. Dulle, K. Volk, M. Karg,
A. Greiner, H. Schmalz, Angew. Chem. Int. Edit. 2017, 56, 405-408; b)
G. Riess, Prog. Polym. Sci. 2003, 28, 1107-1170.
a) Y. Y. Mai, A. Eisenberg, Chem. Soc. Rev. 2012, 41, 5969-5985; b) F.
H. Schacher, P. A. Rupar, I. Manners, Angew. Chem. Int. Edit. 2012, 51,
7898-7921.
a) H. Qiu, V. A. Du, M. A. Winnik, I. Manners, J. Am. Chem. Soc. 2013,
135, 17739-17742; b) H. B. Qiu, G. Cambridge, M. A. Winnik, I. Manners,
[4]
[5]
[6]
This article is protected by copyright. All rights reserved.