Thieme
Original Article
[13] Archana Synthesis and anticonvulsant activity of newer 5,6-dichlo-
roindolyl thiazoles and their thiazolidinones and formazans. ISST
J App Chem 2018; 9: 1–6
drug phenytoin sodium are depicted in ▶table 2. Compound 13
substituted with 4-hydroxyphenyl ring have shown equipotent ac-
tivity to phenytoin sodium (80 %). Compound 10 having phenyl
group as substituent showed 60% activity and compound 12 sub-
stituted with 4-N,N-dimethyl phenyl ring also exhibited same per-
cent inhibition (60 %) of seizures, while compound 11 substituted
with 3-methoxy-4-hydroxyphenyl ring exhibited a potent (70 %)
activity.
[14] Dinnimath BM, Manjunath L, Munishamgowda Y et al. Synthesis and
developing of new thiazolidones and thiotriazole-indoles as potent
anticonvulsant agents. Int J Pharm Res 2013; 5: 78–82
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of new [1,2,4] triazino [5,6-b] indol-3-ylthio-pyrimidines against
leishmania donovani. Eur J Med Chem 2010; 45: 2359–2365
[16] Sridhar SK, Pandeya SN, Stables JP et al. Anticonvulsant activity of
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Conflict of Interest
[17] Archana Srivastava VK, Kumar A. Synthesis of newer thiadiazolyl and
thiazolidinonyl quinazolin-4(3H)-ones as potential anticonvulsant
agents. Eur J Med Chem 2002; 37: 873–882
There is no conflict of interest among the authors of this manuscript.
[18] Murtuja S, Shaquiquzzaman M, Amir M. Design, Synthesis, and
screening of hybrid benzothiazolyl-oxadiazoles as anticonvulsant
agents. Letters in Drug Design and Discovery 2018; 15: 398–405
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Archana, Saini S. Synthesis and Anticonvulsant Studies… Drug Res